Abbott Research Group - UW Chemical and Biological Engineering
Laboratory for Molecular Engineering
Department of Chemical and Biological Engineering
Self-Assembly of Non-Natural Peptides
Unmasked the influence of amphiphilicity of thiolated ß-peptide nanorods on ordering within monolayers formed on gold surfaces (Chem. Mat. 2007). These studies compared the self-assembly of two sequence isomers. Two-dimensional ordering was shown to be dictated by the ß-peptide sequence, where only a globally amphiphilic ß-peptide formed a well-ordered monolayer; its non-amphiphilic sequence isomer did not.